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Figure 6.
Figure 6. The Putative Thiostrepton/Micrococcin–Binding
Site in the GTPase-Associated RegionThe sites of mutations
conferring resistance to thiostrepton and micrococcin are
clustered around a cleft between the RNA and the proline-rich
helix in the L11 N-terminal domain. Residues implicated in
thiostrepton binding (A1067, A1095, and Pro-22) are highlighted
in red and labeled. The position of Tyr-61, which is protected
by thiostrepton in protein footprinting experiments, is also
indicated. Other residues highlighted in red are those that
confer micrococcin resistance (see text for details). The figure
was made with RIBBONS ([5]).
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