Figure 4 - full size

Figure 4.
Figure 4. The lipophilic cavity. (a) Stereoscopic view displaying all hydrophobic side-chains inside the b-cup. (b) Stereoscopic view of the three independent monomers superimposed using the program LSQKAB (CCP4 suite). The monomers are color-coded red (monomer A), yellow (monomer B) and blue (monomer C). Regions of high flexibility are A90-D100, I119-C125, F152-L163. Side-chains with the largest rmsd among the three monomers (see the text) are displayed with the same color code (Figures generated with RIBBONS).[42]