Figure 4 - full size

Figure 4.
Figure 4. Schematic representation of the recognition by S15 on rRNA, possible implications in 30S assembly and comparison with mRNA binding. S15 is schematized in green with its two RNA binding sites numbered 1 and 2. The first one recognizes a particular backbone geometry (the three-way junction in rRNA and the pseudoknot fold in mRNA). The second one recognizes an analogous G-U/G-C motif in both RNAs. In 16S rRNA, binding induces a conformational adjustment (widening of the deep groove), denoted by a red star, that is most likely required for subsequent 30S assembly steps (for example, S18 binding).