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Figure 3.
Fig. 3. A, relative positions of the variable light and
heavy chains in the dimers of the unliganded Fab and the
Fab-peptide complex. B, conformational differences in hyper
variable loop H3 between the unliganded MN12H2 Fab and the
Fab-peptide complex. C, superposition of the cavity floor
residues of the unliganded and liganded MN12H2 Fabs. For these
figures the corresponding V[L] chains of the monoclinic
unliganded Fab and the liganded Fab structures were overlaid as
a dimer as described in Fig. 2. Light and heavy chain residues
of the liganded Fab are shown in green and magenta. Unliganded
Fab residues and their corresponding backbone positions are
shown in yellow. These figures were produced with MOLSCRIPT and
RASTER3D (30, 31).
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