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Figure 3.
Fig. 3. Injection i.p. of recombinant PAL enzyme reduces
plasma phenylalanine in the ENU2/2 mouse (y axis is logarithmic
scale) over time (x axis) (P < 0.05). Reduction of plasma
phenylalanine by PAL shows a dose-response relationship (z
axis). Data are normalized to the control (sham-treated) values
for each animal at each point. Data depicted are the average of
five paired series. The range of control (100%) values was
390-2,013 µmol/liter for animals receiving 2 units of PAL,
572-1,488 µmol/liter for animals receiving 20 units, and
504-1,474 µmol/liter for animals receiving 100 units.
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