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Figure 3.
Figure 3 Histone tails between DNA gyres. The H2B (red) and
H3 (blue) N-terminal tails pass through channels in the DNA
superhelix (white) formed by aligned minor grooves. b, H3 tail
segment in minor-groove channel. The H3 tail sequence HRYRP
passes through the juxtaposed minor grooves of SHL -7 (DNA
terminus) and SHL1 (DNA centre). The electron density (magenta)
clearly identifies the conformation of these amino acids. c, H4
tail bound to the H2A-H2B dimer. The electrostatic surface of
the nucleosome core particle shows an intensely negatively
charged region (bright red) near the centre of its exposed
protein face. Amino acids 16-25 of the H4 tail lie on this
region of the H2A-H2B dimer, which contains 7 clustered acidic
side chains. The orientation of the particle is as for Fig. 1d .
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