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Figure 4.
Fig. 4. Quinone binding pockets and active site residues. (A)
Stereoview of the Q[P] binding site shows Q[P] is bound in a
polar pocket likely positioned just above the membrane bilayer.
(B) Stereoview of the Q[D] site shows Q[D] is in a relatively
apolar pocket within the membrane bilayer. (C) Binding site for
the physiological inhibitor oxaloacetate adjacent to the FAD.
Oxaloacetate lies beneath the isoalloxazine ring of the flavin.
The flavin ring and inhibitor are shown superimposed onto a
2|F[o]|  |F[c]|
map contoured at 1  . The
adenine has been omitted for clarity. Side chains that appear to
interact directly with the inhibitor are labeled.
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