Figure 1 - full size

Figure 1.
Fig. 1. Details of the interactions that stabilize the loop at the C terminus of the duplicated helix. (a) L20 (the design template). (b) L20/R63A in the presence of guanidinium. Distances (black) are shown in Å; in green are the corresponding distances in the WT structure. The superimposed F[o] - F[c] difference map contoured at 3.3 (red) defines the position of the ligand.