Figure 8 - full size

Figure 8.
Figure 8. Surface representation of the active site of PfSAHH. A molecule of 2-F-noraristeromycin (2-F-NAM) is modeled into the Ado-binding site of PfSAHH. Superposition was done with respect to the adenine rings of Ado and 2-F-NAM. The carbon atoms and a fluorine atom are shown in pink and green, respectively. A surface depression that exists specifically in PfSAHH, but not in HsSAHH, is indicated by stars.