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Figure 7.
Top, domains of tetrameric p53 interacting with those of
Pirh2. UBE2D2-Pirh2 RING domain orientations are based on the
crystal structure of the homologous complex formed between UBCH7
and the c-Cbl RING domain^20. Bottom, active site cysteine of
UBE2D2, charged with ubiquitin, is shown in red.
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