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Figure 7.
Figure 7. A model of ADR1-DBD bound to the UAS1, showing both
zinc fingers and the N-terminal region. The position of the
zinc fingers on the GAGG binding site is modeled from the
Zif268−DNA complex and specific base contacts determined from
change-of-specificity experiments^1, ^3. The structure of the
N-terminal region is the average structure taken from the global
fold of ADR1-DBD and positioned with relation to the binding
site on the basis of NOE contacts observed in the 3D ^15N-edited
NOESY spectra.
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