Figure 7 - full size

Figure 7.
Figure 7. Comparison of Q[i]-site residues and ligands in structures 1PPJ and Y21. The two structures were superimposed based on cytochrome b residues 32-51, 79-99, 113-145, 161-201, and 263-300. The backbone is shown for parts of transmembrane helices A (pink), D (red), and E (green), in color for 1PPJ and gray for Y21; as well as some of the linker region preceding helices A and D. Relevant side-chains are drawn with bonds and carbon atoms the same color as the backbone. Water molecules are shown as red spheres for 1PPJ and pink spheres for Y21. Antimycin from 1PPJ is shown as a purple ball-and stick figure with red oxygen atoms, while ubiquinone from structure Y21 is yellow. Note the relatively invariant positions of the backbone and side-chains, and the positioning of the ubiquinone ring over the amide moiety of antimycin.