Figure 7 - full size

Figure 7.
FIG. 7. Proposed mechanism of inactivation for ALR by DCS or LCS. DCS and LCS are converted to an identical final aromatic adduct through transamination, transamination, and tautomerization steps. The DCS- or LSC-bound PLP intermediate following the transamination step can be racemized to each counterpart by the same reaction as used for the true substrates.