Figure 6 - full size

Figure 6.
Figure 6. Schematic Models of the Mechanism of F-Actin Interaction with Tβ Proteins When Bound to More Than One Actin Monomer
(A) Possible interactions with TTβ (black) and actobindin (Act, purple). G-actin and F-actin protomers are depicted in green and light blue, respectively.
(B) Possible interactions of ciboulot (Cib, yellow) with actin. In this mechanism, at the barbed end of the filament (+), the N-terminal helices are proposed to be released by the actin G- to –F-actin transition, while, at the pointed end (−), the C-terminal cap is unaffected by the state of actin. Red crosses signify capped filaments (Irobi et al., 2004).