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Figure 6.
Figure 6. Schematic Models of the Mechanism of F-Actin
Interaction with Tβ Proteins When Bound to More Than One Actin
Monomer (A) Possible interactions with TTβ (black) and
actobindin (Act, purple). G-actin and F-actin protomers are
depicted in green and light blue, respectively. (B)
Possible interactions of ciboulot (Cib, yellow) with actin. In
this mechanism, at the barbed end of the filament (+), the
N-terminal helices are proposed to be released by the actin G-
to –F-actin transition, while, at the pointed end (−), the
C-terminal cap is unaffected by the state of actin. Red crosses
signify capped filaments (Irobi et al., 2004).
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