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Figure 6.
Figure 6. A representation of the proposed interaction of
GM2-AP with a lipid monolayer. The open structure of GM2-AP1 is
depicted as ribbon model (generated in DINO) with its apolar and
mobile loops colored purple. Basic amino acid side-chains in
this region are shown in blue (K57, K65, R138, K154), and the
two tryptophan residues (W63, W131) are shown in yellow. In
structure A, the apolar loop is shown to interface with a PC
monolayer. Structure B represents the observed crystal complex
of GM2-AP1.
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