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Figure 6.
Figure 6 Comparison of the ubiquitin binding site (blue
residues) on Tsg101 UEV (yellow) with models for the two
distinct ubiquitin binding sites (purple) on the Ubc13/Mms2
heterodimer (gray) (VanDemark et al., 2001). To create the
figure, Tsg101 UEV was superimposed on either the Ubc13 E2 (A)
or the Mms2 UEV (B) subunits of the Ubc13/Mms2 heterodimer. The
figure illustrates the fact that the Ub binding surface on
Tsg101 is distinct from previously characterized Ub binding
sites on either E2 or UEV domains, but does roughly correspond
to the Mms2 binding site on Ubc13.
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