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Figure 6.
Figure 6. Thr106 of p38 plays a crucial role in the p38-SB
inhibitor interactions. (a) In the native p38 structure, Thr106
forms an interaction with a water molecule. (b) In the
p38-inhibitor complex, Thr106 rotates around x1 for about 120°
and participates in the nearby hydrogen-bonding network that
also involves His107. b strands in the N-terminal domain are
colored green.
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