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Figure 5.
Moderately selective compound 16 binds to mouse iNOSox
similarly to bulky quinazoline and aminopyridine inhibitors and
induces the Gln-open conformation. Residues are colored
according to Figure 2. The F[o] – F[c] electron density map
contoured at 3 (blue
mesh) is shown around the inhibitor (pink).
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