|
Figure 5.
FIGURE 5. Binding site architectures and electron density
of fucose (A), the type II H-trisaccharide (B), the blood group
A-tetrasaccharide analogue (C), and the Lewis^y antigen (D)
bound to SpX-1. Electron density maps are
maximum-likelihood(17)/  [A] (27) weighted
2F[obs] - F[calc] electron density maps contoured at 1 (0.39,
0.48, 0.23, and 0.28 electrons/Å^3) for the fucose, type
II blood group H-trisaccharide, blood group A-tetrasaccharide
analogue, and Lewis^y antigen complexes, respectively. Relevant
residues involved in binding are shown in gray stick
representation and labeled.
|
