Figure 5 - full size

Figure 5.
Figure 5. Primer extension by Pol and Pol from T or C opposite the dA adduct. DNA substrate is shown above; asterisk indicates the site of either an A or an dA residue in the template; Y at the primer terminus denotes either T or C opposite the undamaged A or the dA template residue. Each protein (1 nM) was incubated with DNA substrate (10 nM) and all four dNTPs (50 M).