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Figure 5.
Figure 5. (a) Superposition of the recognition loops
(residues 180-190 shown) of TA (green), AT (red) and AU (blue).
DNA from TA is shown in grey. In AU, the loops from each monomer
have moved apart approximately 0.6 Å. (b) van der Waals
contacts made by Thr186 to the center step of TA. The C^g-methyl
of Thr186 (blue) lies in a pocket formed by the C5-methyl of
thymine (orange), the O4 of thymine and the N6 of adenine (red).
(c) Center step contacts in AT, shown as in (b). Even when
adenine and thymine are switched in AT, a similar set of
hydrophobic contacts is made.
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