Figure 5 - full size

Figure 5.
Figure 5. Electrostatic Surface DiagramsSurface representations for the Ecm1-AdoHcy-cap complex in 180° orientations. Electrostatic potential is shown on the Ecm1 surface and in contours at 2.0 k[b]T (blue) and −2.0 k[b]T (red) to highlight the complementary electrostatics observed for AdoMet (negative to counter the AdoMet positive charge) and cap-binding sites (positive to counter the negative phosphate charge). Electrostatic potential map and figure were prepared using GRASP (Nicholls et al., 1991).