Figure 5 - full size

Figure 5.
Figure 5. Interactions between the enzyme and the bound cofactor from a single subunit in ALDH2. The bound NAD^+ molecule is shown using a ball-and-stick representation and colored according to atom type. Dashed lines indicate potential hydrogen-bonding interactions <3.3 Å, except for the interaction between the peptide nitrogen of Trp168 and the nicotinamide phosphate which is 3.6 Å (see text). (Figure was produced using the program MOLSCRIPT [52].)