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Figure 4.
Fig. 4. Conservation of binding-site residues amongst
flavivirus family members. Black background denotes nonsimilar
substitutions, and the shaded rectangles bring attention to
residues where increased variability is observed. Numbering for
YF is noted and is used throughout the manuscript to describe
all MTase residues. Residues with side chains within
hydrogen-bonding distance of GTP are marked with an asterisk
(*). Residues with backbone carbonyl groups interacting with the
conserved water and the guanine ring are marked with the symbol
(@).
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