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Figure 4.
FIGURE 4. The mjAK/L-threonine structure reveals two sets
of threonine binding sites. Each L-threonine is positioned in
the binding site by interactions between its functional groups
and the enzyme. Inset A, the binding modes of two threonines at
the A-B dimer interface site. This inset is rotated by 90°
to provide a clearer view of the two bound threonines. Inset B,
the binding of a single threonine with lower occupancy at the
C-D dimer interface site. This inset is rotated by 180° to
show the binding interactions at this site. Inset C,
representative binding of threonine at the weaker secondary
sites in each monomer, located adjacent to the active site.
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