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Figure 4.
Van der Waals interactions between PR and LPV lost due to the
I47A mutation. The distances are represented as dashed lines
with numbers in angstroms. (A) Wild-type PR (1MUI) complexed
with LPV. Segmentation of LPV into P2, P1, P1[prime prime or
minute], and P2[prime prime or minute] subsites is depicted. (B)
PR3 (I47A) complexed with LPV. (Thin gray lines) Superimposition
of LPV as bound to the wild-type PR.
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