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Figure 4.
FIGURE 4. Stereo images of structures representing
different states during the reaction cycle of amylomaltase. A,
empty active site at pH 5.6. The residues Asp-293, Glu-340,
Asp-395, and Gln-256 are indicated. B, acarbose (ACR) complex as
determined by Przylas et al. (22). The subsites +1 and -1 are
indicated. C, acarbose covalent intermediate-4-deoxyglucose
complex. D, covalent intermediate with acarbose. Possible
hydrolytic water molecules are indicated as spheres.
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