|
Figure 4.
FIGURE 4. X-ray structure and dynamics properties of the
dimeric interface of the regulatory domain. A, structural
comparison of the superimposed C[  ]atoms of HP-RR^r
(yellow), the active ArcA^N (orange, PDB accession code 1XHF),
and the active PhoB^N (green, PDB accession code 1ZES). Major
structural deviations occur from a 4-amino acid deletion as
shown within the blue circle. B, both electrostatic and
hydrophobic interactions of the dimeric interface are shown. A
network of ionic interactions is formed between Glu^83 ( 4),
Asp^93 (  5), and Arg^108 ( 5). The
core interactions of the hydrophobic patch consisting of Val^84
( 4), Phe^87 ( 4),
Ala^104 ( 5), Ala^107 ( 5), and
Ala^111 ( 5) are also shown
between dimeric interface. C, dynamic properties of HP-RR^r.S^2
and R[ex] values are depicted. Order parameters, S^2, are
colored onto the ribbon structure. According to increasing S^2,
residues are colored from red (S^2 < 0.70) to yellow (S^2 >
0.90) in a linear fashion. For the residues with R[ex] > 0.5
s^-1, ribbon diameter (pink color) is increased in a linear
fashion.
|
