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Figure 4.
FIGURE 4. Structure of the allogeneic stimulating peptide,
KPI, complexed to the MHC. The cytochrome P450 derived peptide,
KPIVVLHGY (aqua), sitting in the peptide binding cleft of the
MHC, HLA-B^*3501 (green). The surrounding final 2F[o] - F[c]
electron density for the peptide is shown in mesh format. This
figure shows the positions of key anchor residues (Pro^2 and
Tyr^9) and possible TCR contact residues (Val^4, Val^5, and
His^7).
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