Figure 4.
Fig. 4. Two distinct conformations of glyphosate. Displayed
are the electron densities, contoured at 3 , derived from 1F[o]
– 1F[c] Fourier syntheses to 1.7-Å resolution, omitting
the model of glyphosate during the refinement of the ternary
complexes of CP4 EPSP synthase (Left) and Ala-100–Gly CP4 EPSP
synthase (Right). (Right) The conformation of glyphosate upon
interaction with the Ala-100–Gly CP4 EPSP synthase is
identical to the one observed in the E. coli or Str. pneumoniae
enzymes. (Left) With an Ala residue in position 100, the
glyphosate molecule is 0.6 Å shorter,
mainly because of a rotation around the C 4
N bond next to the carboxyl group.
, derived from 1F[o]
– 1F[c] Fourier syntheses to 1.7-Å resolution, omitting
the model of glyphosate during the refinement of the ternary
complexes of CP4 EPSP synthase (Left) and Ala-100–Gly CP4 EPSP
synthase (Right). (Right) The conformation of glyphosate upon
interaction with the Ala-100–Gly CP4 EPSP synthase is
identical to the one observed in the E. coli or Str. pneumoniae
enzymes. (Left) With an Ala residue in position 100, the
glyphosate molecule is 
0.6 Å shorter,
mainly because of a rotation around the C 
4
N bond next to the carboxyl group.