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Figure 4.
Figure 4. The interface between the bPIX-SH3 domain and the
PAK2-derived peptide. (a) Stereo view of the structure of the
bPIX-SH3/PAK2 complex (red and yellow) which is superimposed on
the structure of the bPIX-SH3 domain (gray). (b) The
simulated-annealed 2F[o] -F[c] electron density map, sliced at
2.5 s, is shown for the PAK peptide (yellow stick
representation). The C^a trace of the bPIX-SH3 domain is shown
in red below the transparent van der Waals representation of the
surface (gray). (c) Close-up view of the entire interface. PAK2
residues are labeled in yellow, and bPIX-SH3 domain residues are
labeled in red. Residues in PAK2 that are essential for the
interaction are labeled in orange.
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