Figure 4 - full size

Figure 4.
Figure 4. Crystal structure of USP7 NTD bound to MDM2 peptide 4. (a) Transparent surface diagram of MDM2-USP7. (b) Detailed interactions between USP7 (light gray) and MDM2 (dark gray). (c) Overlay of MDM2 (blue) and p53 359-PGGS-362 (red) peptides from USP7 complex structures.