Figure 4 - full size

Figure 4.
Figure 4. Crystallographic water molecules in the active site. The same region of the active site is shown as in Figure 2 and Figure 3, with the same color code for protein atoms and organic solvent molecules. Water molecules are superimposed on the trifluoroactyl-Lys-Pro-p-isopropylanilide (pink). The water molecules are color-coded according to the model from which they were taken: XLINK, white; HEX, salmon; ETH, hot pink; TFE1, cyan; TFE2, orange; IPR, light green; IBZ, green; ICY, dark green; ACE, red; DMF, blue; ACN, yellow.