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Figure 4.
Figure 4 Similarity between the reelin subrepeat and the CBM.
(A) Reelin subrepeat B (R3B) and the ligand-binding domain of
bacterial cellulase (1GWL), in surface presentation, viewed from
the same orientation. Their surfaces are color-coded by the type
of residue: red for acidic, blue for basic, and yellow for
aromatic residues. In 1GWL, its bound ligand oligomannose is
shown in a stick model, whereas in R3B the 'ligand-like'
inserted loop from the subrepeat A, with important residues
making direct side-chain contacts, is shown. (B) Stereo
presentation of the close-up view at the subrepeat A–B
interface. R3B residues involved in the recognition of R3A loop
are shown in stick models inside the half-transparent molecular
surface and labeled. Both hydrophobic and hydrogen bonding
interactions are evident. The figure was made using PyMol
(DeLano, 2002).
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