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Figure 4.
Figure 4. Stereo view of a subunit of wild-type
core-streptavidin (PDB ident 1MK5) (pink coil) superposed on
T7-SA (blue coil). Biotin (bound in core-streptavidin) is shown
in ball-and-stick representation. The flexible binding loop in
the biotin complex is shown in violet. The missing residues in
this loop in the open conformation in T7-SA are shown as
transparent coil. The major differences between the wild-type
and T7-SA structures, in addition to the additional residues at
the C terminus, involve the conformation of the flexible binding
loop (residues 45-52) and the conformation of residues 24-26
near the a helix.
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