Figure 4 - full size

Figure 4.
FIGURE 4. Schematic diagram showing hydrogen-bond and salt-bridge interactions of the active-site residues. Putative interactions are shown by dotted lines if the acceptor and donor are less than 3.5 Å apart. The hydrogen bonds associated with the phosphate group of PLP are omitted for clarity. A, hBCATc-ox complexed with gabapentin. B, hBCATc-ox complexed with 4MeVA.