Figure 4 - full size

Figure 4.
Figure 4. Model of the extracellular portion of the DC-SIGN/R tetramer. (a) A side-view of the model tetramer. The boundary of the repeat domain, CRD and carbohydrate (from DC-SIGNR CRD PDB code 1K9J) are shown as well as a view of the model looking down onto the top of the tetramer. (b) A single helical tetramer model is shown with helical breaks in the region near proline residues.