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Figure 4.
Figure 4. Diversity and Similarity in CP Inhibitors,
Cystatin, and Monellin
(A-F) Structures of CP inhibitors
from (A) potato (4CPA [Rees and Lipscomb, 1982]) and (B) leech
(1DTV [Reverter et al., 2000]) are very different from the
structure of mammalian CP inhibitor, (C) latexin. However,
latexin (N-terminal domain, [D]) is structurally related to
proteins in the (E) cystatin (cysteine protease inhibitor,
chicken cystatin) (1CEW [Bode et al., 1988]) and (F) monellin
(sweet-tasting protein) (1MOL [Somoza et al., 1993]) fold family.
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