Figure 4 - full size

Figure 4. Fig. 4. Schematic representation of the functional mechanism of FMO. Only the relevant parts required to explain the function, isoalloxazine, nicotinamide, and methimazole, are shown. Step 1 is seen in the wild type, step 3 is seen in the protein–cofactor complex, and step 5 is seen in the protein–methimazole complex structures.