Figure 4 - full size

Figure 4.
FIG. 4. ROCK and PKN contact sites of RhoA. The contact site I proposed as the main contact site of RhoA with PKN (27) is colored in brown. The common binding site of RhoA for both ROCKI and PKN (contact site II) is highlighted in orange. The sites interacting exclusively with PKN and ROCK are colored in yellow and red, respectively. All of the contact sites were determined using the 4.5-Å threshold.