Figure 4 - full size

Figure 4.
Fig. 4. Backbone traces of GABARAP structure (cyan) superposed by yellow spheres indicating NH groups for residues that experience chemical shift perturbations upon addition of candidate peptide ligands I V in A E, respectively. Three different sphere sizes are used to indicate the different classes of perturbation described in Table II: large sphere, >1 linewidth; medium sphere, approximately 1 linewidth; and small sphere, <1 linewidth. F, space-filled representation of the GABARAP structure colored according to the surface electrostatic potential computed with the program GRASP (25), with orientation identical to that in A E.