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Figure 4.
Figure 4. A ball-and-stick model of the DHS active-site
structure. The N-terminal helix from a third monomer that covers
the pocket entrance is in pale yellow. The orientation and color
scheme of this figure are the same as in Figure 2. For clarity,
only the nicotinamide ring and its adjacent ribose of NAD are
shown. The hydrogen bonds between water molecules and sidechains
of the protein residues are indicated by gray dotted lines;
atoms are shown in standard colours. The N-terminal helix from
the third monomer blocks the access to the active site.
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