Figure 3 - full size

Figure 3. Figure 3. Hydrogen bonding interactions: (A) in the active site cavity. Full occupancy water molecules are shown as green spheres. Partial occupancy water molecules are shown as red spheres. Hydrogen bonds between partial water molecules are drawn in purple. (B) involving P1, P1 , H4, and catalytic aspartate residues. Interatomic distances are given in Å units.