|
Figure 3.
Crystal structure of the GABA[A]R γ2-subunit YECL-pep
complexed with μ2–AP2 (157–435). (A) Ribbon diagram showing
the binding site within the signal-binding domain of μ2–AP2
complexed with a peptide corresponding to GABA[A]R γ2-subunit
residues 362–371 (gold). (B) Surface representation of the γ2
peptide-binding interface with μ2–AP2, including an overlay
with the endocytic motif of EGFR (turquoise) to compare binding
of the two motifs.
|
