Figure 3.
Figure 3. The N-terminus of the helix moves toward the center
of the protein, with the main chain atoms from W59 and A60 of
the mutant moving by 1.28-1.74 Å (dotted lines). (Inset)
The C[ ]trace
of the E60A mutant (cyan) is shown against the surface rendering
of wild-type FKBP12 (purple), which is partially cut away to
reveal the protein core.
]trace
of the E60A mutant (cyan) is shown against the surface rendering
of wild-type FKBP12 (purple), which is partially cut away to
reveal the protein core.