Figure 3 - full size

Figure 3.
Figure 3: Tertiary interactions defining TPP riboswitch structure and accessibility to the binding pocket. a, Interaction between J3/2 and P2, mediated by the HMP ring. b, Stabilization of the J2-4 junction by two stacked tetrads (in space-filling representation). c, Interactions between L5 and P3 mediated by three K^+ ions (red spheres). d, Surface representation of RNA and accessibility to the TPP-binding pocket. TPP is depicted in a stick and mesh representation.