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Figure 3.
Figure 3. Crystal Structure of the Complex between 22-mer
siRNA and Aa-Ago
(A) A view of the crystal structure of the
complex between externally bound 22-mer siRNA and Aa-Ago. The
color codes of the various domains and linkers of Aa-Ago are as
follows: N domain, pink; L1 linker, green; PAZ domain, cyan; L2
linker, yellow; Mid domain, pink; PIWI domain, cyan; and PIWI
box, red. The siRNA is shown in beige, except for the 2 nt
overhang at one end, which is colored red. The backbone
phosphorus atoms are colored yellow.
(B) The view in (A)
rotated by 90° along the z axis.
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