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Figure 3.
Figure 3. A: Stereo diagram of a close-up of the putative
active site of TM1246 superimposed on the lgPurL structure shown
in ribbon representation. The sulfate ions are from the lgPurL
structure. The start and end regions of the glycine-rich loop in
both the structures are labeled in red. B: Stereo diagram of a
close-up of the lgPurL ADP-binding site superimposed on the
smPurL structure shown in ribbon representation. The ADP moiety
and Mg^2+ ions are from the lgPurL structure. In A and B,
residues are numbered according to TM1246 structure (PDB 1vk3)
and the equivalent residues of lgPurL (PDB 1t3t) are shown in
parentheses.
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