Figure 3 - full size

Figure 3.
Figure 3. Difference in electron density between the double mutant L99G/E108V and WT*. Amplitudes are (F[L99G/E108V]--F[WT*]) and phases are from the refined structure of WT*. The resolution is 2.5 Å. The map is contoured at ±3.5s and is superimposed on the structure of L99G/E108V which, as noted in the text, is close to that of WT*.