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Figure 3.
Figure 3. Shape complementarity at antibody -HEL interfaces.
(a) Molecular surface of H26 viewed at the site that interacts
with HEL in the H26 -HEL complex drawn using GRASP37. Regions
with higher S[c] values22, indicating closer topological match
with HEL, are more blue; regions with topologically uncorrelated
surfaces (S[c] = 0) are white. (b) The same view of H26 as
described in a, showing the location of V[H] residues in contact
with HEL. (c) Molecular surface of H8 viewed at the binding site
for HEL in the H8 -HEL complex. As in a, regions with better
geometric fits to the antigen are more blue. (d) The same view
of H8 as described in c, showing V[H] residues that interact
with HEL.
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